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This is especially impor-tant at lower, environmentally relevant concentrationswhere small changes in dose can result in large changes ineffect. Althougha structured questionnaire could be used to ascertain some information aboutthe participants, the main source of data is by face-to-face or telephone inter-views, with largely open-ended questions to find out about their characteristics,lifestyle habits, opinions, or experiences (other study types almost always usestructured questions). This diagram shows the various types of epitheliaand the region where they are found in the thin limb of the short andlong loops of Henle

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